Comparative evaluation of the efficacy of chitosan and formocresol as medicaments for pulpotomy in primary molars: A clinical pilot study

Nihal R Kothari1Orcid, S K Srinath2Orcid, Sulakshana S3Orcid, Aswathy T4Orcid, Padmapriya S5Orcid


This study evaluated the efficacy of chitosan which is a non toxic, bioactive material with anti microbial and wound healing properties as pulpotomy medicaments in primary teeth.
While both groups showed similar success rate clinically, chitosan had better success rate radiographically.
Chitosan is a safe, biocompatible and effective medicament for pulpotomy in primary molars. Owing to its advantages of chitosan, it can be used as an alternative to formocresol as a pulpotomy agent.


Aim: To compare the clinical and radiographic effectiveness of chitosan and formocresol as pulpotomy medicaments in primary molars. Methods: Children of age 4-8 years old, who were physically and mentally healthy without any known medical history of systemic conditions contraindicating pulp therapy with at least one deep carious primary molars indicated for pulpotomy, were recruited. Pulpotomies were performed on 64 teeth divided into 2 groups, Group A (chitosan) and Group B (formocresol), followed by stainless steel crowns. Evaluation of clinical and radiological success was done at 1, 3 and 6 months follow up. Chi Square Test was used to compare the clinical and radiological parameters between study groups at different time intervals (p < 0.05) Results: Clinical success rate in both groups was 96.6% and radiographic success rate in chitosan was 96.6%, but formocresol was 89.6%. Conclusions: Chitosan was found to be an effective medicament for pulpotomy in primary molars. While chitosan also showed improved success rate compared to formocresol, it was not statistically significant.

Keywords: Chitosan; Formocresol; Pulpotomy

Author Affiliations

  1. Post graduate, Department of Pedodontics, Government Dental College And Research Institute, Bengaluru-560002(✉ Correspondence:
  2. Professor and Head, Department of Pedodontics, Government Dental College And Research Institute, Bengaluru-560002
  3. Assistant Professor, Department of Pedodontics, Government Dental College And Research Institute, Bengaluru-560002
  4. Post graduate, Department of Pedodontics, Government Dental College And Research Institute, Bengaluru-560002
  5. Post graduate, Department of Pedodontics, Government Dental College And Research Institute, Bengaluru-560002
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Article Info

Contemp Pediatr Dent 2021:2(2):90-100

Received: 02 May 2021

Accepted: 28 June 2021

Online First: 01 July 2021


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					Nihal R Kothari, S K Srinath, Sulakshana S, Aswathy T, Padmapriya S. Comparative evaluation of the efficacy of chitosan and formocresol as medicaments for pulpotomy in primary molars: A clinical pilot study. Contemp Pediatr Dent 2021:2(2):90-100.

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