Storage medium for avulsed teeth: A narrative review

Rutuja Shinde¹image, Dinesh Rao2 image, Sunil Panwar3 image, Remi RV4 image

Highlights

Immediate replantation is essential for achieving optimal treatment success and a favorable prognosis in avulsed permanent teeth.

The biological properties of storage mediums are critical for preserving the viability, clonogenic capacity, and mitogenic potential of periodontal ligament cells.

Milk is a preferred storage medium due to its satisfactory performance, widespread availability, and cost-effectiveness in emergency situations.

Abstract

Dental avulsion is the most severe type of traumatic tooth injury, resulting in the complete displacement of the tooth from its socket in the alveolar bone. Immediate replantation of an avulsed permanent tooth is recommended for successful treatment and a good prognosis. However, replantation is not always feasible. The biological properties of the storage medium, which must preserve the viability, clonogenic capacity, and mitogenic potential of the periodontal ligament (PDL) cells, are crucial for successful reimplantation. If the root surface dries out excessively due to prolonged extraoral time before replantation, the damaged PDL cells can trigger an inflammatory response across the root surface, leading to ankylosis. There are various types of storage media, both synthetic and natural. Therefore, selecting the appropriate storage medium in an emergency is critical for improving the outcome of teeth that cannot be immediately replanted. This review examines research on various storage media for avulsed teeth, focusing on their properties and effectiveness, based on articles from electronic databases.

Keywords: Dental Trauma; Periodontal Ligament; Storage media; Tooth Avulsion; Traumatic Dental Injuries

Author Affiliations

  1. Postgraduate Student, Department of Pediatric Dentistry, Pacific Dental College and Hospital, India
  2. Professor, Department of Pediatric Dentistry, Pacific Dental College and Hospital, India (Correspondence:pedodinesh2003@yahoo.co.in)
  3. Professor, Department of Pediatric Dentistry, Pacific Dental College and Hospital, India
  4. Senior Lecturer, Department of Pediatric Dentistry, Pacific Dental College and Hospital, India
  1. Yadav S, Sisodia N, Jha V, Yadav M. Dental exarticulation. Niger J Clin Pract 2015;18:426-428
  2. Hamilton F, Hill F, Mackie I. Investigation of lay knowledge of the management of avulsed permanent incisors. Dent Traumatol 1997;13:19-23
  3. Moazzami F, Asheghi B, Sahebi S. Effect of four different media on periodontal ligament cells viability of dry-stored dog teeth. J Dent 2017;18:24
  4. Osmanovic A, Halilovic S, Kurtovic‐Kozaric A, Hadziabdic N. Evaluation of periodontal ligament cell viability in different storage media based on human PDL cell culture experiments—A systematic review. Dent Traumatol 2018;34:384-393
  5. Lee W, Stover S, Rasoulianboroujeni M, Sherman K, Fahimipour F, Dashtimoghadam E et al. The efficacy of commercial tooth storage media for maintaining the viability of human periodontal ligament fibroblasts. Int Endod J 2018;51:58-68
  6. Ashkenazi M, Sarnat H, Keila S. In vitro viability, mitogenicity and clonogenic capacity of periodontal ligament cells after storage in six different media. Dent Traumatol 1999;15:149-156
  7. Khinda VI, Kaur G, Brar GS, Kallar S, Khurana H. Clinical and practical implications of storage media used for tooth avulsion. Int J Clin Pediatr Dent 2017;10:158
  8. Adnan S, Khan FR. Storage media for avulsed teeth: a review. J Pak Dent Assoc 2014;23:54-60
  9. Kaur A. Storage Media for Avulsed Tooth: A Brief Review of Literature. Journal of MAR Dental Sciences 2023;7:1-9
  10. Khan M, Sharma M. Comparison of efficacy of different storage media for an avulsed tooth. Int J Appl Dent Sci 2020;6:528-531
  11. Poi WR, Sonoda CK, Martins CM, et al. Storage media for avulsed teeth: a literature review. Braz Dent J 2013;24:437-445
  12. Udoye CI, Jafarzadeh H, Abbott PV. Transport media for avulsed teeth: a review. Aust Endod J 2012;38:129-136
  13. de Borba MG, de Alencar AHG, de Figueiredo JAP, Estrela C. Storage media for avulsed teeth: review of literature. Rev Odonto Ciência 2014;29:63-67
  14. Mabudi A, Hoshyari N. Different Storage Medium for Avulsed Teeth: A Literature Review. J Mazandaran Univ Med Sci 2019;29:117-129
  15. Venugopal M. Recent advances in transport medium for avulsed tooth: A review. Amrita J Med 2022;18:37-44
  16. Surana P, Doifode D, Gopal R, Aafreen S. Recent Advances in Storage Media for Avulsed Tooth-A review. Int J Clin Prev Dent 2018;5:73-78
  17. Navin H, Veena A, Rakesh C, Prasanna K. Advances in storage media for avulsed tooth: A review. Int J Prev Clin Dent 2015;2:41-47
  18. Andersson L, Andreasen JO, Day P, Heithersay G, Trope M, Diangeliset AJ et al. International Association of Dental Traumatology guidelines for the management of traumatic dental injuries: 2. Avulsion of permanent teeth. Dent Traumatol 2012;28:88-96
  19. Blomlöf L, Otteskog P, Hammarström L. Effect of storage in media with different ion strengths and osmolalities on human periodontal ligament cells. Scand J Dent Res 1981;89:180-187
  20. Gomes MCB, Westphalen VPD, Westphalen FH, Silva Neto U, Fariniuk LF, Carneiro E. Study of storage media for avulsed teeth. Braz J Dent Traumatol 2009;1:69-76
  21. Goswami M, Chaitra T, Chaudhary S, Manuja N, Sinha A. Strategies for periodontal ligament cell viability: An overview. J Conserv Dent 2011;14:215-222
  22. Pearson RM, Liewehr FR, West LA, Patton WR, McPherson III JC, Runner RR. Human periodontal ligament cell viability in milk and milk substitutes. J Endod 2003;29:184-185
  23. Malhotra N. Current developments in interim transport (storage) media in dentistry: an update. Br Dent J 2011;211:29-33
  24. Lekic P, Kenny D, Barrett E. The influence of storage conditions on the clonogenic capacity of periodontal ligament cells: implications for tooth replantation. Int Endod J 1998;31:137-140
  25. Khademi A, Saei S, Mohajeri M, Mirkheshti N, Ghassami F, Torabi nia N et al. A new storage medium for an avulsed tooth. J Contemp Dent Pract 2008;9:25-32
  26. Andreasen J, Borum M, Andreasen F. Replantation of 400 avulsed permanent incisors. 3. Factors related to root growth. Dent Traumatol 1995;11:69-75
  27. Courts FJ, Mueller WA, Tabeling HJ. Milk as an interim storage medium for avulsed teeth. Pediatr Dent 1983;5:183-186
  28. Hammarström L, Pierce A, Blomlöf L, Feiglin B, Lindskog S. Tooth avulsion and replantation—a review. Dent Traumatol 1986;2:1-8
  29. Huang S-C, Remeikis NA, Daniel JC. Effects of long-term exposure of human periodontal ligament cells to milk and other solutions. J Endod 1996;22:30-33
  30. Kokkali V, Bendgude V, Sharangpani G. Comparative evaluation of post-traumatic periodontal ligament cell viability using three storage media. Eur Arch Paediatr Dent 2017;18:209-214
  31. Abdallah A, Gamal A, Elyazeed G, Hamid M. Egg White-Milk Mixture as a Novel Biological Storage Media for Avulsed teeth Periodontal Ligament Cells: An In-Vitro Study. J Dent Oral Care Med 2017;3:101-110
  32. Burdock G. Review of the biological properties and toxicity of bee propolis (propolis). Food Chem Toxicol 1998;36:347-363
  33. Kujumgiev A, Tsvetkova I, Serkedjieva Y, Bankova V, Christov R, Popov S. Antibacterial, antifungal and antiviral activity of propolis of different geographic origin. J Ethnopharmacol 1999;64:235-240
  34. Al-Shaher A, Wallace J, Agarwal S, Bretz W, Baugh D. Effect of propolis on human fibroblasts from the pulp and periodontal ligament. J Endod 2004;30:359-361
  35. Martin MP, Pileggi R. A quantitative analysis of Propolis: a promising new storage media following avulsion. Dent Traumatol 2004;20:85-89
  36. Pileggi R, Antony K, Johnson K, Zuo J, Holliday LS. Propolis inhibits osteoclast maturation. Dent Traumatol 2009;25:584-588
  37. Casaroto AR, Hidalgo MM, Sell AM, Franco Sl, Cuman RKN, Moreschi E et al. Study of the effectiveness of propolis extract as a storage medium for avulsed teeth. Dent Traumatol 2010;26:323-331
  38. Abdelbaseer N, Khattab N, Mahmoud M. Evaluation of the efficacy of propolis as storage media for avulsed teeth. Egypt Dent J 2022;68:2115-2121
  39. Özan F, Tepe B, Polat ZA, Er K. Evaluation of in vitro effect of Morus rubra (red mulberry) on survival of periodontal ligament cells. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;105:66-69
  40. Mori GG, Nunes DC, Castilho LR, Moraes IG, Poi WR. Propolis as storage media for avulsed teeth: microscopic and morphometric analysis in rats. Dent Traumatol 2010;26:80-85
  41. Nwangwa EK, Aloamaka CP. Regenerative effects of coconut water and coconut milk on the pancreatic β–cells and cyto architecture in alloxan induced diabetic wistar albino rats. Am J Trop Med Public Health 2011;1:137-146
  42. Mantena SK, Jagadish, Badduri SR, Siripurapu KB, Unnikrishnan MK. In vitro evaluation of antioxidant properties of Cocos nucifera Linn. water. Food Nahrung 2003;47:126-131
  43. Ali SA-H, Al-Jundi S, Mhaidat N, Awawdeh L, Naffa R. Effect of coconut water concentration on survival of bench-dried periodontal ligament cells. Int J Clin Pediatr Dent 2011;4:9-13
  44. Gopikrishna V, Thomas T, Kandaswamy D. A quantitative analysis of coconut water: a new storage media for avulsed teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;105:e61-e65
  45. Thomas T, Gopikrishna V, Kandaswamy D. Comparative evaluation of maintenance of cell viability of an experimental transport media “coconut water” with Hank’s balanced salt solution and milk, for transportation of an avulsed tooth: An in vitro cell culture study. J Conserv Dent 2008;11:22
  46. Hwang JY, Choi SC, Park J-H, Kang SW. The use of green tea extract as a storage medium for the avulsed tooth. J Endod 2011;37:962-967
  47. Dreosti IE. Bioactive ingredients: antioxidants and polyphenols in tea. Nutr Rev 1996;54:51-58
  48. Elbling L, Weiss R-M, Teufelhofer O, et al. Green tea extract and (−)‐epigallocatechin‐3‐gallate, the major tea catechin, exert oxidant but lack antioxidant activities. FASEB J 2005;19:1-26
  49. Jung IH, Yun JH, Cho AR, Kim CS, Chung WG, Choi SH. Effect of (-)-epigallocatechin-3-gallate on maintaining the periodontal ligament cell viability of avulsed teeth: a preliminary study. J Periodontal Implant Sci 2011;41:10-16
  50. Jain D, Dasar PL, Nagarajappa S. Natural products as storage media for avulsed tooth. Saudi Endod J 2015;5:107-113
  51. Anačkov G, Božin B, Zorić L, et al. Chemical composition of essential oil and leaf anatomy of Salvia bertolonii Vis. and Salvia pratensis L.(Sect. Plethiosphace, Lamiaceae). Molecules 2008;14:1-9
  52. Masaki H, Sakaki S, Atsumi T, Sakurai H. Active-oxygen scavenging activity of plant extracts. Biol Pharm Bull 1995;18:162-166
  53. Sivropoulou A, Nikolaou C, Papanikolaou E, Kokkini S, Lanaras T, Arsenakis M. Antimicrobial, cytotoxic, and antiviral activities of Salvia fructicosa essential oil. J Agric Food Chem 1997;45:3197-3201
  54. Ozan F, Polat ZA, Tepe B, Er K. Influence of storage media containing Salvia officinalis on survival of periodontal ligament cells. J Contemp Dent Pract 2008;9:17-24
  55. Kim D, Kang K-H. Anti-inflammatory and anti-bacterial potential of mulberry leaf extract on oral microorganisms. Int J Environ Res Public Health 2022;19:4984
  56. Tîrziu I, Lautaru A, Rabontu AG, Popescu GS, Ienciu A, Manea D. Biochemical contents of mulberry fruits 2020
  57. Dimitrijevic D, Kostic D, Paunovic D, et al. Antimicrobial activity and the quantitative analyses of phenolic compounds and heavy metals of red mulberry extracts (Morus rubra L.) from Serbia. Stud Univ Babes-Bolyai Chem 2022;67:195-208
  58. Ozan F, Tepe B, Polat ZA, Er K. Evaluation of in vitro effect of Morus rubra (red mulberry) on survival of periodontal ligament cells. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;105:e66-e69
  59. Kawase T, Okuda K, Momose M, Kato Y, Yoshie H, Burns DM. Enamel matrix derivative (EMDOGAIN®) rapidly stimulates phosphorylation of the MAP kinase family and nuclear accumulation of smad2 in both oral epithelial and fibroblastic human cells. J Periodontal Res 2001;36:367-376
  60. Gestrelius S, Andersson C, Lidström D, Hammarström L, Somerman M. In vitro studies on periodontal ligament cells and enamel matrix derivative. J Clin Periodontol 1997;24:685-692
  61. Van der Pauw MT, Van den Bos T, Everts V, Beertsen W. Enamel matrix‐derived protein stimulates attachment of periodontal ligament fibroblasts and enhances alkaline phosphatase activity and transforming growth factor β1 release of periodontal ligament and gingival fibroblasts. J Periodontol 2000;71:31-43
  62. Fridström M, Schollin J, Crossner CG. Evaluating Emdogain® and healing of replanted teeth using an intra‐individual experimental–control study design. Dent Traumatol 2008;24:299-304
  63. Wang YC, Yu RC, Chou CC. Growth and survival of bifidobacteria and lactic acid bacteria during the fermentation and storage of cultured soymilk drinks. Food Microbiol 2002;19:501-508
  64. Scalabrini P, Rossi M, Spettoli P, Matteuzzi D. Characterization of Bifidobacterium strains for use in soymilk fermentation. Int J Food Microbiol 1998;39:213-219
  65. Côvre LM, Caliente EA, Sonoda CK, Brandini DA, Poi WR. The effect of soy and whole milk as a means to store avulsed teeth: A histometric study. Dent Traumatol 2021;37:81-89
  66. Silva EJ, Rollemberg CB, Coutinho-Filho TS, Krebs RL, Zaia AA. Use of soymilk as a storage medium for avulsed teeth. Acta Odontol Scand 2013;71:1101-1104
  67. Trope M, Friedman S. Periodontal healing of replanted dog teeth stored in Viaspan, milk and Hank’s balanced salt solution. Dent Traumatol 1992;8:183-188
  68. Babaji P, Melkundi M, Devanna R, SB S, Chaurasia VR, VP G. In vitro comparative evaluation of different storage media (hank’s balanced salt solution, propolis, Aloe vera, and pomegranate juice) for preservation of avulsed tooth. Eur J Dent 2017;11:71-75
  69. Vidal A, Fallarero A, Peña BR, et al. Studies on the toxicity of Punica granatum L.(Punicaceae) whole fruit extracts. J Ethnopharmacol 2003;89:295-300
  70. Seeram NP, Adams LS, Henning SM, et al. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. J Nutr Biochem 2005;16:360-367
  71. Chidambara Murthy KN, Jayaprakasha GK, Singh RP. Studies on antioxidant activity of pomegranate (Punica granatum) peel extract using in vivo models. J Agric Food Chem 2002;50:4791-4795
  72. Aggarwal BB, Shishodia S. Suppression of the nuclear factor‐κB activation pathway by spice‐derived phytochemicals: reasoning for seasoning. Ann NY Acad Sci 2004;1030:434-441
  73. Tavassoli-Hojjati S, Aliasghar E, Babaki FA, et al. Pomegranate juice (Punica granatum): a new storage medium for avulsed teeth. J Dent (Tehran) 2014;11:225-232
  74. Fani M, Kohanteb J. Inhibitory activity of Aloe vera gel on some clinically isolated cariogenic and periodontopathic bacteria. J Oral Sci 2012;54:15-21
  75. Fulzele P, Baliga S, Thosar N, Pradhan D. Evaluation of Aloevera gel as a storage medium in maintaining the viability of periodontal ligament cells-An in vitro study. J Clin Pediatr Dent 2016;40:49-52
  76. Pattamapun K, Ruchikeeratikul P, Handagoon S, Chaiyasuk K, Bovonratanavait A. Effect of aloe vera gel on periodontal tissue after avulsion Available from: https://iadr.confex.com/iadr/2006Brisb/techprogram/abstract_81583.htm
  77. Sharma M. In vitro periodontal ligament cell viability in different storage media. Braz Dent J 2016;27:408-411
  78. Diarra MS, Hassan YI, Block GS, Drover JC, Delaquis P, Oomah BD. Antibacterial activities of a polyphenolic-rich extract prepared from American cranberry (Vaccinium macrocarpon) fruit pomace against Listeria spp. LWT 2020;123:109056
  79. Anegundi RT, Paritosh SN, Tavargeri A, Patil S, Trasad V, Battepati P. Novel herbal storage media for exarticulated teeth. Int J Contemp Med Res 2016;3:729-732
  80. Purnima A, Koti B, Thippeswamy A, et al. Antiinflammatory, analgesic and antipyretic activities of Mimusops elengi Linn. Indian J Pharm Sci 2010;72:480-490
  81. Kumar KN, Kumar CS, Rao VVN. The use of herbal extracts of Ocimum sanctum and Mimusops elengi as a novel storage media for the avulsed tooth. J Adv Med Dent Sci Res 2018;6:1-9
  82. Sójka M, Kołodziejczyk K, Milala J, et al. Composition and properties of the polyphenolic extracts obtained from industrial plum pomaces. J Funct Foods 2015;12:168-178
  83. Michalska A, Wojdyło A, Łysiak GP, Figiel A. Chemical composition and antioxidant properties of powders obtained from different plum juice formulations. Int J Mol Sci 2017;18:176
  84. Hooshmand S, Kumar A, Zhang JY, Johnson SA, Chai SC, Arjmandi BH. Evidence for anti-inflammatory and antioxidative properties of dried plum polyphenols in macrophage RAW 264.7 cells. Food Funct 2015;6:1719-1725
  85. Vyas T, Sood P, Kaur M. Antioxidants in oral diseases and future prospects and their application in dentistry. J Adv Med Dent Sci Res 2018;6:53-62
  86. Bijlani S, Shanbhog R, Godhi BS, Talwade P, Tippeswamy H. An in vitro evaluation of ice apple water, Aloe vera, and propolis as a storage medium to preserve viability of human periodontal ligament fibroblasts. J Indian Soc Pedod Prev Dent 2022;40:195-200
  87. Bijlani S, Shanbhog RS. An in vitro evaluation of ice apple as a novel storage medium to preserve the viability of human periodontal ligament fibroblasts. Int J Clin Pediatr Dent 2022;15:699-705
  88. Dhimole P, Bhayya DP, Gupta S, Kumar P, Tiwari S, Pandey S. Evaluation of the efficacy of neem (Azadirachta indica) and turmeric (Curcuma longa) as storage media in maintaining periodontal ligament cell viability: An in vitro study. J Indian Soc Pedod Prev Dent 2019;37:140-145
  89. Nabavizadeh M, Abbaszadegan A, Khodabakhsi A, Ahzan S, Mehrabani D. Efficiency of castor oil as a storage medium for avulsed teeth in maintaining the viability of periodontal ligament cells. J Dent 2018;19:28-35
  90. Alacam T, Görgül G, Omürlü H, Can M. Lactate dehydrogenase activity in periodontal ligament cells stored in different transport media. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996;82:321-323
  91. Ashkenazi M, Marouni M, Sarnat H. In vitro viability, mitogenicity and clonogenic capacities of periodontal ligament fibroblasts after storage in four media supplemented with growth factors. Dent Traumatol 2001;17:27-35
  92. Pileggi R, Dumsha TC, Nor JE. Assessment of post‐traumatic PDL cells viability by a novel collagenase assay. Dent Traumatol 2002;18:186-189
  93. Krasner P, Person P. Preserving avulsed teeth for replantation. J Am Dent Assoc 1992;123:80-88
  94. Ashkenazi M, Marouni M, Sarnat H. In vitro viability, mitogenicity and clonogenic capacity of periodontal ligament cells after storage in four media at room temperature. Dent Traumatol 2000;16:63-70
  95. Khan M, Sharma M. Comparison of efficacy of different storage media for an avulsed tooth. Int J Appl Dent Sci 2020;6:528-531
  96. Chandha MH. Extra alveolar storage media for tooth autotransplants and replants. J Med Nus 2006;27:64-67
  97. Sigalas E, Regan JD, Kramer PR, Witherspoon DE, Opperman LA. Survival of human periodontal ligament cells in media proposed for transport of avulsed teeth. Dent Traumatol 2004;20:21-28
  98. Franklin S. Weine endodontic therapy. 1st ed. Auflage: Mosby, St Louis 2004
  99. Chamorro MM, Regan JD, Opperman LA, Kramer PR. Effect of storage media on human periodontal ligament cell apoptosis. Dent Traumatol 2008;24:11-16
  100. Pohl Y, Tekin U, Boll M, Filippi A, Kirschner H. Investigations on a cell culture medium for storage and transportation of avulsed teeth. Aust Endod J 1999;25:70-75
  101. Bazmi BA, Singh AK, Kar S, Mubtasum H. Storage media for avulsed tooth-A review. Indian J Multidiscip Dent 2013;3:1-10
  102. Pritchett JW. L-dopa in the treatment of nonunited fractures. Clin Orthop Relat Res 1990:293-300
  103. Partovi M, Sadeghein A, Azizi E, Ostad SN. Mitogenic effect of L-dopa on human periodontal ligament fibroblast cells. J Endod 2002;28:193-196
  104. Ebenezar AV, T M, Priya J. Addition of L-dopa to HBSS in enhancing the maintenance of cell viability of Periodontal Ligament (PDL) cells: An In-Vitro Study. J Clin Diagn Res 2014;8:ZC79-80
  105. Trope M, Friedman S. Periodontal healing of replanted dog teeth stored in Viaspan, milk and Hank’s balanced salt solution. Endod Dent Traumatol 1992;8:183-188
  106. Rajendran P, Varghese NO, Varughese JM, Murugaian E. Evaluation, using extracted human teeth, of Ricetral as a storage medium for avulsions–an in vitro study. Dent Traumatol 2011;27:217-220
  107. Souza BDM, Lückemeyer DD, Felippe WT, Simões CMO, Felippe MCS. Effect of temperature and storage media on human periodontal ligament fibroblast viability. Dent Traumatol 2010;26:271-275
  108. Zeissler-Lajtman A, Connert T, Kühl S, Filippi A. Cling film as storage medium for avulsed teeth. An in vitro pilot study. Swiss Dent J 2017;127:954-959
  109. Nabi S, Kavikumar V, Tahir A. Storage media for avulsed tooth–A review. Eur J Biomed Pharm Sci 2018;5:130-133
  110. Poi WR, Sonoda CK, Martins CM, et al. Storage media for avulsed teeth: a literature review. Braz Dent J 2013;24:437-445
  111. Sottovia AD, Sottovia Filho D, Poi WR, Panzarini SR, Luize DS, Sonoda CK. Tooth replantation after use of Euro-Collins solution or bovine milk as storage medium: a histomorphometric analysis in dogs. J Oral Maxillofac Surg 2010;68:111-119
  112. Schwartz O, Andreasen J. Cryopreservation of mature teeth before replantation in monkeys:(I) Effect of different cryoprotective agents and freezing devices. Int J Oral Surg 1983;12:425-436
  113. Buttke TM, Trope M. Effect of catalase supplementation in storage media for avulsed teeth. Dent Traumatol 2003;19:103-108
  114. Pettiette M, Hupp J, Mesaros S, Trope M. Periodontal healing of extracted dogs’ teeth air‐dried for extended periods and soaked in various media. Dent Traumatol 1997;13:113-118
  115. Ji LL, Song G, Jiang LM, et al. Evaluation of conditioned medium from placenta-derived mesenchymal stem cells as a storage medium for avulsed teeth: An in vitro study. Dent Traumatol 2021;37:73-80
  116. Saini D, Gadicherla P, Chandra P, Anandakrishna L. Coconut milk and probiotic milk as storage media to maintain periodontal ligament cell viability: an in vitro study. Dent Traumatol 2017;33:160-164
  117. Caglar E, Peker S, Durhan MA, Kulan P, Kuscu OO, Pisiriciler RA et al. Quantitative Analysis of a Probiotic Storage Media for Avulsed Teeth. Acta Stomatol Croat 2015;49:21-26
  118. Cehreli SB, Gurpinar AO, Onur AM, Dagli FT. In vitro evaluation of casein phosphopeptide‐amorphous calcium phosphate as a potential tooth transport medium: viability and apoptosis in L929 fibroblasts. Dent Traumatol 2008;24:314-319
  119. Mousavi B, Alavi SA, Mohajeri MR, Mirkheshti N, Ghassami F, Mirkheshti N. Standard oral rehydration solution as a new storage medium for avulsed teeth. Int Dent J 2010;60:379-382
  120. Singh S, Kini S, Pai S, HR R, Purayil TP. Survival of human periodontal ligament fibroblast cells in Cornisol and HBSS for transportation of avulsed teeth: a comparative ex vivo study. Acta Odontol Scand 2021;79:112-117
  121. Lynch SE, Williams RC, Polson AM, et al. A combination of platelet-derived and insulin-like growth factors enhances periodontal regeneration. J Clin Periodontol 1989;16:545-548
  122. Thoyalil M, Belchada DK, Devi KB, Ravi RV, Uchummal MM, Parikkal R. The Comparative Analysis of the Effectiveness of Four Different Storage Media (Placentrex, Propolis 10%, Pomegranate Juice 5%, and Hank’s Balanced Salt Solution) in Preserving the Viability of Periodontal Ligament Cells: An In Vitro Study. Cureus 2023;15:1-10

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Contemp Pediatr Dent 2024:5(2):53-70

Received: 23 February 2024

Accepted: 11 May 2024

Online First: 25 May 2024

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					Rutuja Shinde, Dinesh Rao, Sunil Panwar, Remi RV. Storage medium for avulsed teeth: A narrative review. Contemp Pediatr Dent 2024:5(2):53-70.
				
			

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