Dental management and behavioral considerations in pediatric patients with attention-deficit/hyperactivity disorder: A narrative review

Divya Rajpurohit¹ image, Dinesh Rao2 image, Sunil Panwar3 image, Surbhi Sharma4 image, Manan Phalke5 image

Highlights

Children with ADHD face higher risk of caries, trauma, and bruxism due to behavioral challenges and medication side effects.

Effective dental care requires tailored strategies including short visits, simple instructions, and positive reinforcement.

Multidisciplinary collaboration among dentists, caregivers, and healthcare providers is essential for comprehensive care.

Abstract

Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental condition that affected children’s behavior, learning, and oral health. This narrative review aimed to synthesize current evidence on diagnostic considerations, comorbidities, behavioral manifestations, and dental management strategies in pediatric patients with ADHD. A structured electronic search was performed in PubMed/MEDLINE, Lilacs, BBO, and SciELO databases for English-language publications from 1971 to 2022. Of 145 records initially identified, 54 met the inclusion criteria. All studies were critically appraised by two independent reviewers to assess methodological rigor and relevance to pediatric dental practice. Children with ADHD were consistently reported to have an elevated risk of dental caries, traumatic dental injuries, and bruxism, largely attributable to behavioral challenges, poor oral hygiene practices, and side effects of stimulant medications. ADHD was also frequently associated with comorbid psychiatric and functional impairments that further complicated dental management. Effective care should be facilitated by short, well-timed appointments, simplified instructions, use of positive reinforcement, and coordination with caregivers and healthcare providers. A comprehensive understanding of the behavioral, medical, and pharmacological dimensions of ADHD is indispensable for pediatric dental practitioners. Individualized, multidisciplinary approaches are essential to optimize oral health outcomes and overall quality of life in children with ADHD.

Keywords: Attention-Deficit Hyperactivity Disorder; Behavior; Dental Management; Narrative Review; Oral Health; Pediatric Dentistr

Author Affiliations

  1. Postgraduate Student, Department of Pediatric Dentistry, Pacific Dental College & Hospital, India

  2. Professor, Department of Pediatric Dentistry, Pacific Dental College & Hospital, India (Correspondence:pedodinesh2003@yahoo.co.in)

  3. Professor, Department of Pediatric Dentistry, Pacific Dental College & Hospital, India

  4. Senior Lecturer, Department of Pediatric Dentistry, Pacific Dental College & Hospital, India

  5. Senior Lecturer, Department of Pediatric Dentistry, Pacific Dental College & Hospital, India

  1. Pelham WE, Foster EM, Robb JA. The economic impact of attention-deficit/hyperactivity disorder in children and adolescents. J Pediatr Psychol 2007;32:711-727
  2. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 3rd ed. Washington, DC: American Psychiatric Association;1980. p.205-224
  3. Kessler RC, Üstün TB. The world mental health (WMH) survey initiative version of the world health organization (WHO) composite international diagnostic interview (CIDI). Int J Methods Psychiatr Res 2004;13:93-121
  4. Copeland WE, Angold A, Costello EJ, Egger H. Prevalence, comorbidity, and correlates of DSM-5 proposed disruptive mood dysregulation disorder. Am J Psychiatry 2013;170:173-179
  5. Gillberg C, Gillberg IC, Rasmussen P, Kadesjö B, Söderström H, Råstam M, et al. Co-existing disorders in ADHD: implications for diagnosis and intervention. Eur Child Adolesc Psychiatry 2004;13:80-92
  6. Lange KW, Reichl S, Lange KM, Tucha L, Tucha O. The history of attention deficit hyperactivity disorder. Atten Defic Hyperact Disord 2010;2:241-255
  7. Baethge C, Goldbeck-Wood S, Mertens S. SANRA: a scale for the quality assessment of narrative review articles. Res Integr Peer Rev 2019;4:1-7
  8. Tannock R. Attention deficit hyperactivity disorder: advances in cognitive, neurobiological, and genetic research. J Child Psychol Psychiatry 1998;39:65-79
  9. Morrison JR, Stewart MA. A family study of the hyperactive child syndrome. In: Rutter M, Hersov L, editors. Child psychiatry: modern approaches. Oxford: Blackwell Scientific;1971. p.123-135
  10. Malhi P, Singhi P. Spectrum of attention deficit hyperactivity disorder in children among referrals to psychology services. Indian Pediatr 2000;37:1258-1260
  11. Stewart MA, deBlois SC, Cummings C. Psychiatric disorder in the parents of hyperactive boys and those with conduct disorder. J Child Psychol Psychiatry 1980;21:283-292
  12. Biederman J, Faraone SV, Keenan K, Benjamin J, Krificher B, Moore C, et al. Further evidence for family-genetic risk factors in attention deficit hyperactivity disorder: patterns of comorbidity in probands and relatives. Arch Gen Psychiatry 1992;49:728-738
  13. Faraone SV, Perlis RH, Doyle AE, Smoller JW, Goralnick JJ, Holmgren MA, et al. Molecular genetics of attention-deficit/hyperactivity disorder. Biol Psychiatry 2005;57:1313-1323
  14. Bobb AJ, Castellanos FX, Addington AM, Rapoport JL. Molecular genetic studies of ADHD: 1991 to 2004. Am J Med Genet B Neuropsychiatr Genet 2006;141:551-565
  15. Li Z, Chang SH, Zhang LY, Gao L, Wang J. Molecular genetic studies of ADHD and its candidate genes: a review. Psychiatry Res 2014;219:10-24
  16. Sieg KG, Gaffney GR, Preston DF, Hellings JA. SPECT brain imaging abnormalities in attention deficit hyperactivity disorder. Clin Nucl Med 1995;20:55-60
  17. Milberger S, Biederman J, Faraone SV, Chen L, Jones J. Is maternal smoking during pregnancy a risk factor for attention deficit hyperactivity disorder in children? Am J Psychiatry 1996;153:1138-1142
  18. Schlotz W, Jones A, Phillips DI, Gale CR, Robinson SM, Godfrey KM. Lower maternal folate status in early pregnancy is associated with childhood hyperactivity and peer problems. J Child Psychol Psychiatry 2010;51:594-602
  19. Nigg JT, Hinshaw SP. Parent personality traits and psychopathology associated with antisocial behaviors in childhood ADHD. J Child Psychol Psychiatry 1998;39:145-159
  20. Edwards MC, Schulz EG, Long N. The role of the family in the assessment of ADHD. Clin Psychol Rev 1995;15:375-394
  21. Barkley RA. ADHD, self-regulation, and time: toward a more comprehensive theory. J Dev Behav Pediatr 1997;18:271-279
  22. Teeter PA, Semrud-Clikeman M. Integrating neurobiological, psychosocial, and behavioral paradigms: a transactional model for ADHD. Arch Clin Neuropsychol 1995;10:433-461
  23. Biederman J, Newcorn J, Sprich S. Comorbidity of ADHD with conduct, depressive, anxiety, and other disorders. Am J Psychiatry 1991;148:564-573
  24. Kring AM, Johnson SL. Abnormal psychology: the science and treatment of psychological disorders. Hoboken: John Wiley & Sons;2022
  25. Sucksdorff M, Lehtonen L, Chudal R, Suominen A, Joelsson P, Gissler M, et al. Preterm birth and poor fetal growth as risk factors of ADHD. Pediatrics 2015;136:599-608
  26. Robberecht H, Verlaet AA, Breynaert A, De Bruyne T, Hermans N. Magnesium, iron, zinc, copper and selenium status in ADHD. Molecules 2020;25:4440
  27. Villagomez A, Ramtekkar U. Iron, magnesium, vitamin D, and zinc deficiencies in children with ADHD. Children (Basel) 2014;1:261-279
  28. Kozielec T, Starobrat-Hermelin B, Kotkowiak L. Deficiency of certain trace elements in children with hyperactivity. Psychiatr Pol 1994;28:345-353
  29. Konofal E, Lecendreux M, Deron J, Marchand M, Cortese S, Zaïm M, et al. Effects of iron supplementation on ADHD in children. Pediatr Neurol 2008;38:20-26
  30. El-Baz FM, Youssef AM, Ramadan D, Youssef WY. Association between zinc/ferritin levels and parent Conner’s scores in ADHD. Eur Psychiatry 2019;62:68-73
  31. Kostiner H, Kats L, Kot-Limon N, Dolev E, Blumer S. Methylphenidate and mandibular bone characteristics in children with ADHD. Children (Basel) 2022;9:1276
  32. Uwitonze AM, Ojeh N, Murererehe J, Atfi A, Razzaque MS. Zinc adequacy and oral health. Nutrients 2020;12:949
  33. Skalny AV, Mazaletskaya AL, Ajsuvakova OP, Bjorklund G, Skalnaya MH, Chao CJJ, et al. Serum zinc, copper, and minerals in children with ADHD. J Trace Elem Med Biol 2020;58:126445
  34. Ghanizadeh A, Berk M. Zinc for ADHD: a systematic review. Eur J Clin Nutr 2013;67:122-124
  35. Yang R, Zhang Y, Gao W, Lin N, Li R, Zhao Z. Blood trace elements in children with ADHD: a case-control study. Biol Trace Elem Res 2019;187:376-382
  36. Kiddie JY, Weiss MD, Kitts DD, Levy-Milne R, Wasdell MB. Nutritional status in children with ADHD: a pilot study. Int J Pediatr 2010;2010:767318
  37. Mikami AY, Huang-Pollock CL, Pfiffner LJ, McBurnett K, Hangai D. Social skills differences among ADHD types in chatroom task. J Abnorm Child Psychol 2007;35:509-521
  38. Barkley RA, Fischer M. Emotional impulsiveness and life impairment in hyperactive adults. J Am Acad Child Adolesc Psychiatry 2010;49:503-513
  39. Hinshaw SP, Melnick SM. Peer relationships in boys with ADHD and aggression. Dev Psychopathol 1995;7:627-647
  40. DuPaul GJ, McGoey KE, Eckert TL, VanBrakle J. Preschool ADHD impairments in behavioral, social, and school functioning. J Am Acad Child Adolesc Psychiatry 2001;40:508-515
  41. Faraone S, Biederman J, Monuteaux MC. Diagnostic continuity of ADHD from child to adolescent. J Atten Disord 2002;6:5-13
  42. Wilens TE, Biederman J, Brown S, Tanguay S, Monuteaux MC, Balke C, et al. Comorbidity and functioning in preschool and school-age ADHD. J Am Acad Child Adolesc Psychiatry 2002;41:262-268
  43. Swain JE, Scahill L, Lombroso PJ, King RA, Leckman JF. Tourette syndrome and tic disorders: decade review. J Am Acad Child Adolesc Psychiatry 2007;46:947-968
  44. Lee SS, Humphreys KL, Flory K, Liu R, Glass K. ADHD and substance use: meta-analytic review. Clin Psychol Rev 2011;31:328-341
  45. Cole WR, Mostofsky SH, Larson JG, Denckla B, Mahone EM. Motor signs and ADHD in boys and girls. Neurology 2008;71:1514-1520
  46. Harvey WJ, Reid G, Bloom GA, Staples K, Grizenko N, Mbekou, et al. Physical activity in boys with and without ADHD. Adapt Phys Activ Q 2009;26:131-150
  47. Goodman R. The strengths and difficulties questionnaire: research note. J Child Psychol Psychiatry 1997;38:581-586
  48. Achenbach TM. Manual for the Child Behavior Checklist 4-18 and 1991 profile. Burlington (VT): University of Vermont, Department of Psychiatry;1991
  49. Conners CK. Rating scales in drug studies with children. Psychopharmacol Bull 1973;9:24-29
  50. Berg I, Lucas C, McGuire R. Measuring behavior difficulties using computer-administered scales. Eur Child Adolesc Psychiatry 1992;1:14-23
  51. Felt BT, Biermann B, Christner JG, Kochar P, Harrison RV. Diagnosis and management of ADHD in children. Am Fam Physician 2014;90:456-464
  52. Barkley RA, Fischer M, Smallish L, Fletcher K. Do stimulant treatments contribute to later drug use? Pediatrics 2003;111:97-109
  53. Friedlander AH, Yagiela JA, Paterno VI, Mahler ME. The pathophysiology, medical management, and dental implications of children and young adults having attention-deficit hyperactivity disorder. J Calif Dent Assoc 2003;31:669-678
  54. University of Washington, School of Dentistry. Patients with special needs, dental fact sheet for children [Internet] 2023 [cited 2023 Jun 3] . Available from: https://dental.washington.edu/wp-content/media/sp_need_pdfs/ADHD-child.pdf
  55. Felicetti DM, Julliard K. Behaviors of children with and without attention deficit hyperactivity disorder during a dental recall visit. J Dent Child 2000;67:246-249

Article Info

Contemp Pediatr Dent 2025:6(2):105-122

Received: 25 June 2025

Accepted: 21 August 2025

Online First: 28 August 2025

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					Divya Rajpurohit, Dinesh Rao, Sunil Panwar, Surbhi Sharma, Manan Phalke. Dental management and behavioral considerations in pediatric patients with attention-deficit/hyperactivity disorder: A narrative review. Contemp Pediatr Dent 2025:6(2):105-122
				
			

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